Chao-Tsen Chen
Assistant Professor, Chemistry Research Center 208
Tel: (02) 23630231 ext 2332

Fax:(02) 23636359

chenct@ntu.edu.tw

C.-T. Chen's Group Homepage

Born 1963, Ph.D. University of California-San Diego 1993, Postdoctoral Fellow at California Institute of Technology 1994-1995, Postdoctoral Fellow at Columbia University 1995-1997, Assistant Professor at National Taiwan University 1997-present

Research Interests

1)      Coumarin-based Light Emitters in the application of opotoelectronics.

2)      Development of Fluorescent Probes for the Detection of Heavy Metal Ions, Biologically Important Enzymes, and Carbohydrate-Binding Receptors.

3)      Molecular Recognition of Biomolecules versus Nanostructures.

4)      Synthesis of Mesoporous Materials Based on Molecular Imprinting Approach.

1)       Chen, C.-T.; Chiang, C.-L.; Lin, Y.-C.; Chan, L.-H.; Huang, C.-H.; Chen, C.-T.  ¡§Ortho-Substituent Effect on Fluorescence and Electroluminescence of Arylamino-Substituted Coumarin and Stilbene Org. Lett. 2003, 5, 1261-1264.

2)       Chen, A. P.-C.; Chen,Y.-H.; Liu, H.-P.; Li, Y.-C.; Chen, C.-T.; Liang, P.-H. ¡§Synthesis and Application of a Fluorescent Substrate Analogue to Study Ligand Interactions for Undecaprenyl Pyrophosphate Synthase¡¨ J. Am. Chem. Soc. 2002, 124, 15217-15224.

3)       Li, P.-C.; Wang, T.-S.; Lee, G.-H.; Liu,Y.-H.; Wang, Y.; Chen, C.-T.; Chao, I. ¡§Theoretical Study and X-Ray Determination of Bianthrones:  Long C-C Bond Length and Preferred Gauche Conformation¡¨ J. Org. Chem. 2002, 67, 8002-8009.

4)       Chen, C.-T.; Huang, W.-P. ¡§A Highly Selective Fluoroscent Chemosensor for Lead Ions¡¨ J. Am. Chem. Soc. 2002, 124, 6246-6247.

5)       Liao, J.-H.; Chen, C.-T.; Chou, H.-C.; Cheng, C.-C.; Chou, P.-T.; Fang, J.-M.; Slanina, Z. and Chow, T. ¡§2,7-Bis-(1H-pyrrol-2-yl)ethynyl-1,8-naphthyridine: An Ultrasensitive Fluorescent Probe for Glucopyranoside¡¨ J. Org. Lett. 2002, 4, 3107-3110.

6)       ¡§Conformational Change of E coli Undecaprenyl Pyrophosphate Synthase¡¨ Chen, Y.-H.; Chen, A. P.-C.; Chen, C.-T.; Wang, A. H.-J.; Liang, P. H. J. Biol. Chem. 2002, 277, 7369-7376.

7)       Liao, J.-H.; Chen, C.-T.; Fang, J.-M. ¡§A Novel Phosphate Chemosensor Utilizing Anion Induced Fluorescence Change¡¨ Org. Lett. 2002, 4, 561-564.

8)       Talukdar, S.; Chen, R.-J.; Chen, C.-T.; Lo, L.-C.; Fang, J.-M. ¡§Polymer-Supported Benzotriazoles as Catalysts in the Synthesis of Tetrahydroquinolines by Condensation of Aldehydes with Aromatic Amines¡¨ J. Comb. Chem. 2001, 3, 341.

9)       Lo, L.-C.; Liao, Y.-C.; Kuo, C.-H.; Chen, C.-T. ¡§A Novel Derivatizing Reagent of Alcohols: Application in CD Exciton Chirality Method for Microscale Structural Determination¡¨ Org. Lett. 2000, 2, 683-685.

10)    Chen, C.-T.; Wagner, H.; Still, W. C. ¡§Fluorescent, Sequence-Selective Peptide Detection by Synthetic Small Molecules¡¨ Science 1998, 279, 851-853