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Department of Chemistry

Faculty

FANG, Jim-Min


FANG, Jim-Min
Professor Emeritus, Distinguished Chair Professor
Room A619, Chemistry Building
Fax: +886-2-2363-7812
LAB WEBSITE
NTU SCHOLARS
Research Interest

  • Organic synthesis: synthetic methods and asymmetric catalysis.

  • Chemical biology: biomolecular recognition, natural products and drug discovery.

Career and Service Experiences

  • B.S., 1974, Department of Chemistry, National Taiwan University.

  • Ph.D., 1980, Department of Chemistry, Yale University.

  • Postdoctoral Fellow, 1981-82, Columbia University / Suntory Institute for Bioorganic Research.

  • Associate Professor, 1982-1986; Professor, 1986-2006; Distinguished Professor, 1986-2022; Chair, 1993-1996, Department of Chemistry, National Taiwan University.

  • Adjunct Research Fellow, 2003-2022t, The Genomics Research Center, Academia Sinica.

  • Professor Emeritus, 2022-present, Department of Chemistry, National Taiwan University.

Honors and Awards

  • Award for Outstanding Research, 1987−96 (five times), Invited Principal Investigator, 1997–2003 (twice), National Science Council.

  • Academic Award, Sun Yat-Sen Foundation, (1992).

  • Academic Award, 1997, Chinese Chemical Society (Taipei).

  • Award for Teaching Excellence, 1999 (inaugural), National Taiwan University.

  • Chair Professor, 1999–2004, Foundation for Advancement of Outstanding Scholarship.

  • Award for Outstanding Medical and Pharmaceutical Science and Technology, 2009, TienTe Lee Biomedical Foundation.

  • Academic Award, 2009, Ministry of Education.

  • TBF Chair in Biotechnology, 2014–23, Taiwan Bio-Development Foundation.

  • Academic Contribution Award, 2016, TASCO Group.

  • National Chair Professorship, 2017-2019, Ministry of Education.

  • National Taiwan University Chair Professor, 2020.

Research Content
Selected Publications

  1. Hsu, T.-W.; Fang, J.-M. Effective assay of bacterial transglycosylation by molecular turn-on sensing and secondary-order scattering effect. Analyst, 2021, 146, 5843–5847.

  2. Chang, S.-Y.; Huang, K.-Y.; Chao, T.-L.; Kao, H.-C.; Pang, Y.-H.; Lu. L.; Chiu, C.-L.; Huang, H.-C.; Cheng, T.-J. R.; Fang, J.-M.;* Yang, P.-C.* Nanoparticle composite TPNT1 is effective against SARS-CoV-2 and influenza viruses. Sci. Rep. 2021, 11, 8692.

  3. Chiu, T.-W.; Peng, C.-J.; Chen, M.-C.; Hsu, M.-H.; Liang, Y.-H.; Chiu, C.-H.;* Fang, J.-M.;* Lee, Y. C. Constructing conjugate vaccine against Salmonella Typhimurium using lipid-A free lipopolysaccharide. J. Biomed. Sci. 2020, 27, 89.

  4. Hung, W.-T.; Chen, Y.-T.; Chen, C.-H.; Lee, Y. C.; Fang, J.-M.;* Yang, W.-B.* Flow chemistry system for carbohydrate analysis by rapid labeling of saccharides after glycan hydrolysis. SLAS Technol. 2020, 25, 356–366.

  5. Shie, J.-J.; Fang, J.-M.* Development of effective anti-influenza drugs: congeners and conjugates - a review. J. Biomed. Sci. 2019, 26, 84.

  6. Huang, M.-R.; Hsu, Y.-L.; Lin, T.-C.; Cheng, T.-J.; Li, L.-W.; Tseng, Y.-W.; Chou, Y.-s.; Liu, J.-H.;* Pan, S.-H.;* Fang, J.-M.;* Wong, C.-H. Structure-guided development of purine amide, hydroxamate, and amidoxime for the inhibition of non-small cell lung cancer. Eur. J. Med. Chem. 2019, 181, 111551.

  7. Hong, B.-T.; Cheng, Y.-S. E.; Cheng, T.-J.; Fang, J.-M.* Boronate, trifluoroborate, sulfone, sulfinate and sulfonate congeners of oseltamivir carboxylic acid: synthesis and anti-influenza activity. Eur. J. Med. Chem. 2019, 163, 710−721.

Update: 2023-03-20