國立臺灣大學化學系

Development of new synthetic methods to prepare constrained polycyclic compounds.

• 2020 年迄今任臺灣大學化學系助理教授


• 2018 年日本東京大學擔任講師


• 2011 年日本東京大學擔任助理教授


• 2009 年東京大學博士後研究員


• 2009 年加拿大麥基爾大學博士


• 2005 年加拿大貴湖大學碩士


• 2003 年加拿大貴湖大學學士

• Outstanding Scholar Award, Foundation for the Advancement of Outstanding Scholarship, Taiwan, 2020


• JSPS Postdoctoral Fellowship for Foreign Researchers, 2009


• NSERC Postdoctoral Fellowship, 2009 (declined)

1. Lee, Y.-C.; Chen, Y.-C.; Wu, C.-F.; Yoo, W.-J.* "Synthesis of 1-Substituted Bicyclo[2.1.1]hexan-1-ones via a Sequential SmI₂-Mediated Pinacol Coupling and Acid-Catalyzed Pinacol Rearrangement" Org. Lett. 2024, 26, 9352–9356.


2. Hsu, C.-W.; Wu, C.-F.; Lee, Y.-C.; Yoo, W.-J.* "Synthesis of 2-Substituted Bicyclo[2.1.1]hexan-1-ols via SmI₂-Mediated Reductive Cyclization Reactions" Adv. Synth. Catal. 2024, 366, 4747–4754.


3. Hsu, C.-W.; Lu, Y.-T.; Lin, C.-P.; Yoo, W.-J.* "Synthesis of Bicyclo[2.1.1]hexan-5-ones via a Sequential Simmons–Smith Cyclopropanation and an Acid-Catalyzed Pinacol Rearrangement of α-Hydroxy Silyl Enol Ethers" Adv. Synth. Catal. 2023, 365, 3082–3087.


4. Yoo, W.-J.*; Chen, W.; Nguyen, T. V. Q.; Kobayashi, S.* "One-Pot Synthesis of α,β-Unsaturated γ-Lactones and Lactams via a Sequential trans-Hydroalumination and Catalytic Carboxylation of Propargyl Alcohols and Amines with Carbon Dioxide" Org. Lett. 2020, 22, 2328–2332.


5. Yoo, W.–J.*; Kondo, J.; Rodríguez-Santamaría, J. A.; Nguyen, T. V. Q.; Kobayashi, S.* "Efficient Synthesis of a-Trifluoromethyl Carboxylic Acids and Esters through Fluorocarboxylation of gem-Difluoroalkenes" Angew. Chem. Int. Ed. 2019, 58, 6772–6775.


6. Nguyen, T. V. Q.; Rodríguez-Santamaría, J. A.; Yoo, W.–J.; Kobayashi, S.* "Incorporation of Carbon Dioxide into Phthalides via Ligand-Free Copper-Catalyzed Direct Carboxylation of Benzoxasiloles" Green Chem. 2017, 19, 2501–2505.


7. Cheng, H.–G.; Miguélez, J.; Miyamura, H.; Yoo, W.–J.; Kobayashi, S.* "Integration of Aerobic Oxidation and Intramolecular Asymmetric aza-Friedel–Crafts Reactions with a Chiral Bifunctional Heterogeneous Catalyst" Chem. Sci. 2017, 8, 1356–1359.


8. Nguyen, T. V. Q.; Yoo, W.–J.; Kobayashi, S.* "Effective Formylation of Amines with Carbon Dioxide and Diphenylsilane Catalyzed by Chelating bis(tzNHC) Rhodium Complexes" Angew. Chem. Int. Ed. 2015, 54, 9209–9212.


9. Yoo, W.–J.; Tsukamoto, T.; Kobayashi, S.* "Visible-Light-Mediated Chan–Lam Coupling Reactions of Aryl Boronic Acids and Aniline Derivatives" Angew. Chem. Int. Ed. 2015, 54, 6587–6590.


10. Yoo, W.–J.; Nguyen, T. V. Q.; Kobayashi, S.* "Synthesis of Isocoumarins through Three-Component Couplings of Arynes, Terminal Alkynes, and Carbon Dioxide Catalyzed by an NHC–Copper Complex" Angew. Chem. Int. Ed. 2014, 53, 10213–10217.


11. Yoo, W.–J.; Kobayashi, S.* "Efficient Visible Light-Mediated Cross-Dehydrogenative Coupling Reactions of Tertiary Amines Catalyzed by a Polymer-Immobilized Iridium-Based Photocatalyst" Green Chem. 2014, 16, 2438–2442.


12. Miyamura, H.; Choo, G. C. Y.; Yasukawa, T.; Yoo, W.–J.; Kobayashi, S.* "A Heterogeneous Layered Bifunctional Catalyst for the Integration of Aerobic Oxidation and Asymmetric C–C Bond Formation" Chem. Commun. 2013, 49, 9917–9919.


13. Yuan, H.; Yoo, W.–J.; Miyamura, H.; Kobayashi, S.* "Discovery of a Metalloenzyme-Like Cooperative Catalytic System of Metal Nanoclusters and Catechol Derivatives for the Aerobic Oxidation of Amines" J. Am. Chem. Soc. 2012, 134, 13970–13973.


14. Yoo, W.–J.; Miyamura, H.; Kobayashi, S.* "Polymer-Incarcerated Gold-Palladium Nanoclusters with Boron on Carbon: A Mild and Efficient Catalyst for the Sequential Aerobic Oxidation-Michael Addition of 1,3-Dicarbonyl Compounds to Allylic Alcohols" J. Am. Chem. Soc. 2011, 133, 3095–3103.