國立臺灣大學化學系

• 分子工具的設計及其生化上之應用。


• 氟標記試劑的開發及其在綠色化學之應用。

1983年臺灣大學化學系學士；1985年臺灣大學生化科學研究所碩士；1993年美國哥倫比亞大學化學系博士；1993-1996年美國斯克瑞普斯研究所博士後研究；1996-2005年任臺灣大學化學系副教授；2005年迄今任臺灣大學化學系教授

• 2005 年及2012 年國立臺灣大學教學優良獎

1. Shi, T.-H.; Huang, Y.-L.; Chen, C.-C.; Pi, W.-C.; Hsu, Y.-L.; Lo, L.-C.; Chen, W.-Y.; Fu, S.-L.; Lin, C.-H.* “ Andrographolide and its fluorescent derivative inhibit the main proteases of 2019-nCoV and SARS-CoV through covalent linkage”, Biochem. Biophys. Res. Commun. 2020, 533, 467-473.


2. Cheng W.-C; Liu W.-J; Hu K.-H; Tan Y.-L; Lin Y.-T; Chen W.-A; Lo, L.-C.* ” Rapid Synthesis of a Natural Product-Inspired Uridine Containing Library”, ACS Comb. Sci. 2020, 22, 600-607.


3. Hsu, Y.-H.; Hsu, Y.-L.; Liu, S.-H.; Liao, H.-C.; Lee, P.-X.; Lin, C.-H.; Lo, L.-C.*; Fu. S.-L.* Development of a Bifunctional Andrographolide-Based Chemical Probe for Pharmacological Study”, PLoS ONE 2016, 11, e0152770.


4. Hsu, Y.-L.; Yang, C.-C.; Chou, T.-C.; Tai, C.-H.; Chen, L.-Y.; Fu, S.-L.; Lin, J.-J.*; Lo, L.-C.* “Design, Synthesis, and Evaluation of Cell Permeable Probes for Protein Kinases”, Tetrahedron 2016, 72, 58-68.


5. Hsu, Y.-L.; Nandakumar, M.; Lai, H.-Y.; Chou, T.-C.; Chu, C.-Y.; Lin, C.-H.*; Lo, L.-C.* “Development of Activity-Based Probes for Imaging Human -L-Fucosidases in Cells”, Org. Chem. 2015, 80, 8458-8463.


6. Tai, C.-H.; Lu, C.-P.; Wu, S.-H.*; Lo, L.-C.* “Synthesis and Evaluation of Turn-on Fluorescent Probes for Imaging Steroid Sulfatase Activities in Cells”, Commun. 2014, 50, 6116-6119.


7. Ang, W. J.; Chu, C.-Y.; Chou, T.-C.; Lo, L.-C.*; Lam, Y.* “Application of a Recyclable Fluorous Oxime in the Convenient Synthesis of 3-Amino-1,2-Benzisoxazoles and 4-Amino-1H-2,3-Benzoxazines”, Green Chem. 2013, 15, 780–785.


8. Chu, C.-Y.; Chang, C.-P.; Chou, Y.-T.; Handoko; Hu, Y.-L.; Lo, L.-C.*; Lin, J.-J.* “Development and Evaluation of Novel Phosphotyrosine Mimetic Inhibitors Targeting the Src Homology 2 Domain of Signaling Lymphocytic Activation Molecule (SLAM) Associated Protein”, Med. Chem. 2013, 56, 2841–2949.


9. Susanto, W.; Chu, C.-Y.; Ang, W. J.; Chou, T.-C.; Lo, L.-C.*; Lam, Y.* “Fluorous Oxime Palladacycle: A Precatalyst for Carbon−Carbon Coupling Reactions in Aqueous and Organic Medium” Org. Chem. 2012, 77, 2729–2742.


10. Susanto, W.; Chu, C.-Y.; Ang, W. J.; Chou, T.-C.; Lo, L.-C.*; Lam, Y.* “Development of a Fluorous, Oxime-Based Palladacycle for Microwave-Promoted Carbon-Carbon Coupling Reactions in Aqueous Media” Green Chem. 2012, 14, 77–80.


11. Lu, C.-P.; Ren, C.-T.; Lai, Y.-N.; Wu, S.-H.*; Wang, W.-M.; Chen, J.-Y.; Lo, L.-C.* “Design of a Mechanism-Based Probe for Neuraminidase to Capture Influenza Viruses” Chem. Int. Ed. 2005, 44, 7048–7052.


12. Chu, C.-Y.; Lo, L.-C.* Development of Highly Selective and Sensitive Probes for Hydrogen Peroxide”, Commun. 2003, 2728-2729.


13. Lo, L.-C.*; Pang, T.-L.; Kuo, C.-H.; Chiang, Y.-L.; Wang, H.-Y.; Lin, J.-J.* “Design and Synthesis of Class-Selective Activity Probes for Protein Tyrosine Phosphatases”, Proteome Res. 2002, 1, 35-40.