陳長謙
特聘研究講座
化學館 B408室
傳真: 02-3366-8671
研究興趣
- 生物物理化學
- 蛋白質摺疊與錯誤摺疊
- 細胞膜蛋白的結構及功能
- 生物無機化學與生物催化
- 單碳化學
- 催化劑理性設計
簡歷
- 1957 年加州大學柏克萊校區化工系學士
- 1960 年加州大學柏克萊校區化學博士
- 1960-1961 年任哈佛大學博士後研究員
- 1961-1963 年任加州大學河濱分校化學系助理教授
- 1963-1964 年任加州理工學院化學系助理教授；1964 -1968 年任副教授；1968-1992 年任教授；1992-2001 年任加州理工學院 George Grant Hoag 生物物理化學榮譽講座教授
- 1996-2022 年任香港中文大學名譽教授
- 2007-2022 年任國立臺灣大學化學系特聘講座教授；2010-2022 年任國立臺灣大學化學系特聘研究講座教授
- 2012-2014 年任國立屏東大學榮譽講座教授
- 2013-2023 任國立中興大學講座教授
- 1997-2011 年任中央研究院特聘研究員；2011-2022 任特聘講座
- 1999-2003 年任中央研究院副院長
- 2001-2003 年任基因體醫學國家型科技計畫總主持人
- 2016-2019 年任國立臺灣科技大學榮譽講座教授
榮譽事項
- 1987 年美國物理學會院士
- 1988 年中央研究院院士
- 1991 年美國加州理工學院 ASCIT 教學獎
- 1992 年美國科學促進會會員
- 1993 年香港中文大學 Wilson T.S. Wang 國際傑出教授
- 1994 年美國加州理工學院 Richard M. Badger 傑出教學獎
- 2003 年香港浸會大學榮譽博士
- 2004 年美國生物化學暨分子生物學學會 William C. Rose 獎章
- 2004 年第三世界科學院院士
- 2004 年美國生物物理學會院士
- 2005 年美國生物物理學會生物物理 CBNet 獎章
- 2010 年美國藝術與科學院院士
- 2011 年國際自然科學院院士
- 2016 年臺灣磁共振學會終身成就獎
- 2018 年台灣生物無機化學協會終身成就獎
- 2018 年TASCO化學終身成就獎
- 2019 年印度化學研究協會榮譽院士
代表著作
- Chang, Wei-hau*; Lin, H.-H.; Tsai, I-Kuen;Huang, Shih-Hsin; Chung, Szu-Chi; Tu, I-Ping; Yu, Steve S.-F.*; Chan, Sunney I.* “Copper centers in the cryo-EM structure of particulate methane monooxygenase reveal the catalytic machinery of methane oxidation” J. Am. Chem. Soc. 2021, https://doi.org/10.1021/jacs.1c04082.
- Chan, Sunney I.*; Chuankhayan, Phimonphan; Nareddy, Pavan Kumar Reddy; Tsai, I-Kuen; Tsai, Yi-Fang; Chen, Kelvin H.-C.; Yu, Steve S.-F.; Chen, Chun-Jung*. “The Mechanism of pyrroloquinoline quinone-dependent hydride transfer chemistry from spectroscopic and high-resolution x-ray structural studies of the methanol dehydrogenase from Methylococcus capsulatus (Bath)” J. Am. Chem. Soc. 2021, 143 (9), 3359-3372.
- Chen, Yu-Hsuan; Wu, Chang-Quan; Sung, Pei-Hua; Chan, Sunney I.*; Chen, Peter Ping-Yu*. “Turnover of a methane oxidation tricopper cluster catalyst: Implications for the mechanism of the particulate methane monooxygenase (pMMO)” ChemCatChem 2020, 12, 3088-3096.
- Chan, Sunney I.*; Yu, Steve S.-F.; Liu, Chih-Cheng; Mou, Chung-Yuan*. “Selective oxidation of light alkanes under mild conditions” Current Opinion in Green and Sustainable Chemistry 2020. 22, 39-46.
- Chan, Sunney I.; Yu, Steve S.-F. “Copper protein constructs for methane oxidation” Nature Catalysis 2019, 2, 286-287.
- Chan, Sunney I.; Lee, Seung Jae. “The Biochemistry of Methane Monooxygenases” in Methanotrophs: Microbiology Fundamental and Biotechnological Applications (Microbiology Monographs (Series Ed.: Alexander Steinbüchel))”, (Editor: Eun Yeol Lee), Publisher: Springer Nature, Switzerland, AG. 2019, 32, 71-120.
- Lu, Yu-Jhang; Hung, Mu-Cheng; Chang, Brian T.-A.; Lee, Tsu-Lin; Lin, Zhi-Han; Tsai, I-Kuen; Chen, Yao-Sheng; Chang, Chin-Chuo; Tsai, Yi-Fang; Chen, Kelvin H.-C.; Chan, Sunney I.*; Yu, Steve S.-F.* “The PmoB subunit of the particulate methane monooxygenase (pMMO) in Methylococcus capsulatus (Bath): The CuI sponge and its function” J. Inorg. Biochem. 2019, 196, 110691.
- Yeh, Chen-Hao; Yu, Steve S.-F.; Chan, Sunney I., Jiang, Jyh-Chiang*. “Quantum chemical studies of methane oxidation to methanol on a biomimetic tricopper complex: Mechanistic insights” Chemistry Select 2018, 3. 5113-5122.
- Liu, Chih-Cheng; Janmanchi, Damodar; Wen, Da-Ren; Oung, Jung-Nan; Mou, Chung-Yuan; Yu, Steve S.-F.; Chan, Sunney I.* “Catalytic oxidation of light alkanes mediated at room temperature by a tricopper cluster complex immobilized in mesoporous silica nanoparticles” ACS Sustainable Chem. Eng. 2018, 5, 5431-5440.
- Thiyagarajan, Natarajan; Janmanchi, Damoda; Tsai, Yi-Fang; Wanna, Wondemagegn Hailemichael; Ramu, Ravirala; Chan, Sunney I.*; Zen, Jyh-Myng*; Yu, Steve S.-F.* “A carbon electrode functionalized by a tricopper cluster complex: Overcoming overpotential and production of hydrogen peroxide in the oxygen reduction reaction” Angew.Chem. Int. Ed. 2018, 57, 3612-3616.
- Wang, Vincent C.-C.; Maji, Suman; Chen, Peter P.-Y.; Lee, Hung Kay; Yu, Steve S.-F.; Chan, Sunney I.* “Alkane oxidation: Methane monooxygenases, related enzymes, and their biomimetics” Chem. Rev. 2017, 117, 8574−8621.
- Liu, Chih-Cheng; Mou, Chung-Yuan; Yu, Steve S.-F.; Chan, Sunney I.* “Heterogeneous formulation of the tricopper complex for efficient catalytic conversion of methane into methanol at ambient temperature and pressure” Energy & Environmental Science, 2016, 9, 1361−1374.
- Chan, Sunney I.*; Lu, Yu-Jhang; Nagababu, Penumaka; Maji, Suman; Hung, Mu-Cheng; Lee, Marianne, M.; Hsu, I-Jui; Minh, Pham Dinh; Lai, Jeff C.-H.; Ng, Kok Yoah; Ramalingam; Sridevi; Yu, Steve S.- F.; Chan, Michael K. “Efficient Oxidation of Methane to Methanol by Dioxygen Mediated by Tricopper Clusters” Angew. Chem. Int. Ed. 2013, 52, 3731 –3735.
更新日期: 2023-08-01