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Department of Chemistry


KONG, Kien Voon

KONG, Kien Voon
Associate Professor
Room B580, Chemistry Building
Fax: +886-2-3366-8671
Research Interest

  • Chemistry of metals in medicine - Design of various classes of nanomaterials and organometallic compounds, and studying their mechanism of action in biological systems, leading to novel platforms for the next generation of molecular therapeutics.

  • Chemistry of metals in biosensing and bioimaging - Design of novel sensing and imaging probes for Surface enhanced Raman spectroscopy (SERS) sensing and photoaocustic imaging which can potentially be used as diagnostic tools.

Career and Service Experiences

  • B.Sc. (Hons), 2004, University of Malaya

  • Ph.D., 2009, National University of Singapore

  • RadioChemist, Singapore Radiopharmaceuticals, 2009-2009

  • Scientist, Institute Materials Research and Engineering, 2009-2011

  • Research Fellow, Singapore Bioimaging Consortium, 2011-2014 Senior Research Fellow, 2014-2015

  • National Taiwan University, Assistant Professor, 1st August 2015-30th July 2020.

  • National Taiwan University, Associate Professor, 1st August 2020-Present.

Honors and Awards

  • Undergraduate Scholarship: Kuala Lumpur Stock Exchange (KLSE) Scholarship. Postgraduate Scholarship: NUS Research Scholarship.

Research Content
Selected Publications

  1. Lin, D. Hsieh, C-L. Hsu, K-C. Liao, P-H. Qiu, S. Gong, T. Yong, K-T. Feng, S. Kong, K. V.* Geometrically encoded SERS nanobarcodes for the logical detection of nasopharyngeal carcinoma-related progression biomarkers. Nature communications 2021, 12, 1-16.

  2. Hsu, K-C. Hsieh, C-L. Kong, K. V.* Probing Molecular-Scale Oxidative Generation of Quinone Methides and Their Transformation Using Tip-Enhanced Raman Spectroscopy. The Journal of Physical Chemistry Letters 2021, 12, 1110-1115.

  3. Tan, M.J. Hong, Z-Y. Chang, M-H. Liu, C-C. Cheng, H-F. Loh, X.J. Chen, H. Liao, C-D. Kong, K. V*. Metal carbonyl-gold nanoparticle conjugates for highly sensitive SERS detection of organophosphorus pesticides. Bioelectron. 2017, 96, 167-172.

  4. Gong, T-X. Hong, Z-Y. Chen, C. Tsai, C-Y. Liao, L-D. Kong, K.V.*. Optical Interference-Free Surface-Enhanced Raman Scattering CO-Nanotags for Logical Multiplex Detection of Vascular Disease-Related Biomarkers. ACS Nano, 2017, 11, 3365–3375.

  5. He, Y-J. Tu, T-H. Su, M-K. Yang, C-W. Kong, K. V. Chan, Y-T.* Facile Construction of Metallo-Supramolecular P3HTb-PEO Diblock Copolymers via Coordination and Their Self- Assembled Nanostructures. Am. Chem. Soc. 2017, 139, 4218–4224.


  1. SERS marker conjugates and methods of their preparation. (International Patent. WO 2013180652 A1).

  2. SERS marker conjugates and methods of their preparation. (US patent. 20150126388).

  3. Photoacoustic Imaging Contrast Agent Composition. (International Patent. WO/2015/038066).

  4. Method of Detecting Analysis Having a Thiol Functional Group. (International Patent. WO/2015/041607).

  5. Photoacoustic Imaging Contrast Agent. (International Patent. WO/2015/088444).

  6. Method of detecting Hydrogen Peroxide. (International Patent. WO/2015/038077).

  7. Method for detecting Analyte using SERS and Method of Manufacturing Thereof (International Patent. WO/2014/137291).

  8. SERS marker conjugates and methods of their preparation. (China Patent. CN104507871A).

  9. SERS marker conjugates and methods of their preparation (European patent EP2855360A4).

  10. Photoacoustic Imaging Contrast Agent Composition. (European patent EP3043829 A1).

Update: 2022-01-26