Skip to main content

Department of Chemistry


CHIU, Sheng-Hsien

CHIU, Sheng-Hsien
Room B772, Chemistry Building
Fax: +886-2-3366-1677
Research Interest

  • Design and Syntheses of New Molecular Recognition Systems

  • Development of Supramolecular Polymeric Materials and New Interlocked Molecules

  • Fullerene and Cyclodextrin Chemistry 

Career and Service Experiences

  • B.S., 1994, Department of Chemistry, National Taiwan University

  • Ph.D., 2000, Department of Chemistry and Biochemistry, University of California at Los Angeles

  • Postdoctoral Fellow, 2000-2002, UCLA

  • Assistant Professor, 2002-2006; Associate Professor, 2006-2009; Professor, 2009-present

  • Director, Chemistry Promotion Center 2015-2017

Honors and Awards

  • 2023 NTU Chair Professor.

  • 2022 National Chair Professorship, Ministry of Education.

  • 2017 Distinguished Professor, National Taiwan University.

  • 2017 Academic Award of Ministry of Education.

  • 2015 Outstanding Research Award, Ministry of
    Science and Technology

  • 2015 Distinguished Teaching Award, National Taiwan University.

  • 2009 Outstanding Research Award, National Science Council.

  • 2009 Distinguished Young Chemists Award, Federation of Asian Chemical Societies.

  • 2007 Chinese Chemical Society Outstanding Chemist

  • 2007 Wu Da-You Research Award (National Science

  • 2007 Academia Sinica Award for Young Scholar
    Research Publication.

Research Content
Selected Publications

  1. Tseng, I.-C.; Zhang, M.-X.; Kang, S.-L.; Chiu, S.-H.* “An Anion-Switchable Dual-Function Rotaxane Catalyst” Angew. Chem. Int. Ed. 2023, 62, e202309889.

  2. Tsai, C.-Y., Cheng, H.-T. Chiu, S.-H.* “Improbable Rotaxanes Constructed From Surrogate Malonate Rotaxanes as Encircled Methylene Synthons” Angew. Chem. Int. Ed. 2023, 62, e202308974.

  3. Hsueh, F.-C.; Tsai, C.-Y.; Lai, C.-C.; Liu, Y.-H.; Peng, S.-M.; Chiu, S.-H.* “N-Heterocyclic Carbene–Cu(I) Rotaxanes Mediate Sequential Click Ligations With All Reagents Premixed” Angew. Chem. Int. Ed. 2020, 59, 11278-11282.

  4. Chang, J.-C.; Tseng, S.-H.; Lai, C.-C.; Liu, Y.-H.; Peng, S.-M., Chiu, S.-H.* “Mechanically Interlocked Daisy Chain–Like Structures as Multidimensional Molecular Muscles” Nature Chem20179, 128-134.

  5. Wu, Y.-W.; Tung, S.-T.; Lai, C.-C.; Liu, Y.-H.; Peng, S.-M.; Chiu, S.-H.* “Cyclic [2]Catenane Dimers, Trimers, and Tetramers” Angew. Chem. Int. Ed. 201554, 11745-11749. (Back Cover)

  6. Tung, S.-T.; Lia, C.-C.; Liu, Y.-H.; Peng, S.-M.; Chiu, S.-H.* “Synthesis of a [2]Catenane from the Sodium Ion Templated orthogonal Arrangement of Two Diethylene Glycol” Angew. Chem. Int. Ed. 201352, 13269–13272.

  7. Lin, Y.-H.; Lia, C.-C.; Liu, Y.-H.; Peng, S.-M.; Chiu, S.-H.* “Sodium Ions Template the Formation of Rotaxanes from BPX26C6 and Nonconjugated Amide and Urea Functionalities” Angew. Chem. Int. Ed. 201352, 10231–10236.

  8. Chang, C.-F.; Chuang, C.-J.; Lai, C.-C.; Liu, Y.-H.; Peng, S.-M.; Chiu, S.-H.* “Using Host/Guest Complexation to Fold a Flexible Linear Organic String: Kinetically Controlled Syntheses of [3]Catenanes and a Five-Membered Molecular Necklace” Angew. Chem. Int. Ed. 201251, 10094–10098.

  9. Hsueh, S.-Y.; Ko, J.-L.; Lai, C.-C.; Liu, Y.-H.; Peng, S.-M.; Chiu, S.-H.* “A Metal-Free “Threading-Followed-by Shrinking” Protocol for Rotaxane Synthesis” Angew. Chem. Int. Ed. 201150, 6643–6647.

  10. Hsueh, S.-Y.; Kuo, C.-T.; Lai, C.-C.; Liu, Y.-H.; Hsu, H.-F.; Peng, S.-M.; Chen, C.-H.*; Chiu, S.-H.* “Acid/Base- and Anion-Controllable Organogels Formed From a Urea-Based Molecular Switch” Angew. Chem. Int. Ed.201049, 9170–9173.

  11. Lee, M.-J.; Lai, C.-C.; Liu, Y.-H.; Peng, S.-M.; Chiu, S.-H.* “Two Guest Complexation Modes in a Cyclotriveratrylene-Based Molecular Container” Chem. Commun. 2009, 5814–5816.

  12. Hsu, C.-C.; Chen, N.-C.; Lai, C.-C.; Liu, Y.-H.; Peng, S.-M.; Chiu, S.-H.* “Solvent-Free Synthesis of the Smallest Rotaxane Prepared to Date” Angew. Chem. Int. Ed. 200847, 7475–v7478.

  13. Hsueh, S.-Y.; Cheng, K.-W.; Lai, C.-C.; Chiu, S.-H.* “Efficient Solvent-Free Syntheses of [2]- and [4]Rotaxanes” Angew. Chem. Int. Ed. 200847, 4436–4439.

  14. Huang, Y.-L.; Hung, W.-C.; Lai, C.-C.; Liu, Y.-H.; Peng, S.-M.; Chiu, S.-H.* “Using Acetate Anions to Induce Translational Isomerization in a Neutral Urea-Based Molecular Switch” Angew. Chem. Int. Ed. 200746, 6629–6633.

  15. Hsueh, S.-Y.; Lai, C.-C.; Liu, Y.-H.; Peng, S.-M.; Chiu, S.-H.* “Highly Selective Na+-Templated Formation of [2]Pseudorotaxanes Exhibiting Significant Optical Outputs” Angew. Chem. Int. Ed. 200746, 2013–2017.

  16. Chiu, C.-W.; Lai, C.-C.; Chiu, S.-H.* “Threading-Followed-by-Swelling: A New Protocol for Rotaxane Synthesis” J. Am. Chem. Soc. 2007129, 3500–3501.

  17. Lin, C.-F.; Liu, Y.-H.; Lai, C.-C.; Peng, S.-M.; Chiu, S.-H.* “Precise Facial Control in the Threading of Guests into a Molecular Cage and the Formation of a Turtle-Like Supramolecular Complex” Angew. Chem. Int. Ed. 200645, 3176–3181.

Update: 2024-02-17