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國立臺灣大學化學系

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陳昭岑


陳昭岑
教授
化學館 A607室
電話: 02-3366-4200
傳真: 02-3366-8671
實驗室
學術典藏
研究興趣

  • 開發類固醇共軛光親和/螢光探針,以了解類固醇的生理功能。

  • 開發具核甘核酸特異性之烷化劑,評估作為潛藥物的可能性。

  • 開發兼具造影及藥物輸送分子系統

  • 開發刺激響應材料,包括光電材料/前驅藥物

簡歷

  • 1986 年臺灣大學化學系學士;1993 年美國加州大學聖地牙哥校區化學系博士;1994-1995 年加州理工學院研究員;1995-1997 年哥倫比亞博士後;1997-2003年臺灣大學化學系助理教授; 2003-2006 年臺灣大學化學系副教授;2006年迄今任臺灣大學化學系教授;2009.09-2011.01年任臺灣大學研發處企劃組組長;2011.08-2014.08 年任臺灣大學貴儀中心主任;2016.07-迄今任科技部化學學門召集人

榮譽事項

  • 2004 年中研院年輕學者著作獎

  • 2004 年臺灣大學研究成就獎

  • 2007 年亞洲核心計畫講學獎

  • 2008 年 Thieme Journal Award and the Synlett and Synthesis.

研究內容
代表著作

  1. Singh, R.; Chen, D.-G.; Wang, C.-H.; Lan, Y.-C.; Liu, Y.-H.; Chou, P.-T.*; Chen, C.-T.* “Tailoring C-6-Substituted Coumarin Scaffolds for Novel Photophysical Properties and Stimuli-Responsive Chromism” J. Chem. Phys. B 2021, 125, 41, 11557–11565.

  2. Wang, C.-H.; Liu, Z.-Y.; Huang, C.-H.; Chen, C.-T.*; Meng, F.-Y.; Liao, Y.-C.; Liu, Y.-H.; Chang, C.-C.; Li, E. Y.* and Chou, P.-T.* “Chapter Open for the Excited-State Intramolecular Thiol Proton Transfer in the Room-Temperature Solution” J. Am. Chem. Soc. 2021, 143, 12715−12724.

  3. Lee, Y.-T.; Tseng, P.-C.; Komino, T.; Mamada, M.; Ortiz, R. J.; Leung, M.-k.; Chiu, T.-L.; Lin, C.-F. ; Lee, J.-H. Lee;* Adachi, C.; Chen, C.-T.* and Chen, C.-T.* “Simple molecular-engineering approach for enhancing orientation and out-coupling efficiency of thermally activated delayed fluorescent emitters without red-shifting emission” ACS Appl. Mater. Interfaces 2018, 10, 43842−43849

  4. Chen, H.-Y.; Lin, C.-W.; Chen, C.-T.;* Chen, C.-T.;* Golder, J.; Lan, Y.-B.; Wang, J.-K.* “Polymer side-chain substituents elucidate thermochromism of benzodithiophene-dithiophenylacrylonitrile copolytmers – polymer solubility correlation of thermochromism and photovoltaic performance”Polym. Chem. 2017, 8, 3689.

  5. Lee, Y.-T.; Chang, Y.-T.; Chen, C.-T.*; Chen, C.-T.*“The first aggregation-induced emission fluorophore as a solution processed host material in hybrid white organic light-emitting diodes” J. Mater. Chem. C 2016, 4, 7020.

  6. Chen, C.-H.; Hu, T.-H.; Huang, T.-C.; Chen, Y.-L.; Chen, Y.-R.; Cheng, C.-C*; Chen, C.-T*. “Delineation of G-Quadruplex Alkylation Sites Mediated by 3,6-Bis(1-methyl-4-vinylpyridinium iodide)carbazole-Aniline Mustard Conjugates” Chem. Eur. J. 2015, 21, 17379.

  7. Fu, Y.-H.; Chen, C.-Y.; Chen, C.-T.* “Tuning of hydrogen peroxide-responsive polymeric micelles of biodegradable triblock polycarbonates as a potential drug delivery platform with ratiometric fluorescence signaling” Polym. Chem. 2015, 6, 8132.

  8. Chen, C.-Y.; Chen, C.-T.* “Reaction-Based and Single Fluorescent Emitter-Decorated Ratiometric Nanoprobe to Detect Hydrogen Peroxide” Chem. Eur. J. 2013, 19, 16050.

  9. Weng, J.-H.; Liang, M.-R.; Chen, C.-H., Huang, T.-C.; Chen, Y.-R.; Tong, S.-K.; Lee, S.-P.; Chen, C.-T.*; Chung, B.-c.* “Pregnenolone changes CLIP-170 conformation to promote microtubule polymerization and cell migration” Nature-Chem. Biol. 2013, 9, 636-642.

  10. Lin, Y.-C.; C.-T. Chen* “Alkaline Earth Ion-Induced Coil-Helix-Coil Transition of Lysine-Coumarin-Azacrown Hybrid Foldamers with OFF-OFF-ON Fluorescence Switching” Chem. Eur. J. 2013, 19, 253.

更新日期: 2022-01-25