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國立臺灣大學化學系

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朱忠瀚


朱忠瀚
助理教授
化學館 A521室
電話: 02-3366-8654
傳真: 02-3366-8671
研究興趣
  • 非核糖體肽結構預測
  • 非核糖體肽化學合成
  • 天然物活性篩選
  • 抗菌、抗癌新藥開發
簡歷
  • 2004 年臺灣大學化學系學⼠
  • 2005-2011 美國史克利普斯研究所博⼠
  • 2011-2014 美國耶魯大學博⼠後研究
  • 2014-2019 美國洛克斐勒大學博⼠後研究
榮譽事項
  • 2019 臺灣大學化學系助理教授
  • 2018 美國洛克斐勒大學 博士後協會職涯發展獎
  • 2013 美國耶魯大學 博士後學者旅行獎助金
  • 2011 美國德雷福斯 環境化學博士後獎學金
  • 2004 國立臺灣大學 陳安泰醫師研究獎學金
代表著作

* Denotes equal contribution

  1. Chu, J; Koirala, B; Forelli, N; Vila-Farres, X; Ternei, MA; Ali, T; Colosimo, DA; Brady, SF. “Synthetic-bioinformatic natural product antibiotics with diverse modes of action.”  J. Am. Chem. Soc. 2020142, 14158
  2. Chu, J; Vila-Farres, X; Brady, SF. “Bioactive synthetic-bioinformatic natural product cyclic peptides inspired by nonribosomal peptide synthetase gene clusters from the human microbiome.”  J. Am. Chem. Soc. 2019141, 15737
  3. *Vila-Farres, X; *Chu, J; Ternei, MA; Lemetre, C; Park, S; Perlin, DS; Brady, SF “An optimized synthetic-bioinformatic natural product antibiotic sterilizes multidrug-resistant Acinetobacter baumannii-infected wounds.” mSphere 2018, 3, e00528-17.
  4. *Chu, J; *Vila-Farres, X; Inoyama, D; Gallardo-Macias, R; Jaskowski, M; Satish, S; Freudlich, JS; Brady, SF “Human microbiome inspired antibiotics with improved β-lactam synergy against MDR Staphylococcus aureus.” ACS Infect. Dis. 2018, 4, 33.
  5. Cohen, LJ; Esterhazy, D; Kim, SH; Lemetre, C; Aguilar, RR; Gordon, EA; Pickard, AJ; Cross, JR; Emiliano, AB; Han, SM; Chu, J; Vila-Farres, X; Kaplitt, J; Rogoz, A; Calle, P; Hunter, C; Bitok, JK; Brady, SF “Commensal bacteria make GPCR ligands that mimic human signaling molecules.” Nature 2017, 549, 48.
  6. *Vila-Farres, X; *Chu, J; Inoyama, D; Ternei, MA; Lemetre, C; Cohen, LJ; Cho, W; Reddy, BVB; Zebroski, HA; Freudlich, JS; Perlin, DS; Brady, SF “Antimicrobials inspired by nonribosomal peptide synthetase gene clusters.” J. Am. Chem. Soc. 2017, 139, 1404.
  7. *Chu, J; *Vila-Farres, X; Inoyama, D; Ternei, MA; Cohen, LJ; Gordon, EA; Reddy, BVB; Charlop-Powers, Z; Zebroski, HA; Gallardo-Macias, R; Jaskowski, M; Satish, S; Park S; Perlin, DS; Freudlich, JS; Brady, SF “Discovery of MRSA active antibiotics using primary sequence from the human microbiome.” Nat. Chem. Biol. 2016, 12, 1004.
更新日期: 2021-11-08