馬左仲(Manuel Maestre-Reyna)
助理教授
化學館 B477
傳真:
研究興趣
- Structural enzymology
- Time-resolved structural analysis
- Photochemistry and photobiology of light-driven enzymes
- Developement of X-ray crystallographic techniques and analysis methods
簡歷
- M.S. Biochemistry, 2005, Department of Biology, Valencia University, Spain
- Research Assitant, 2006, Department of Chemistry, Philipps University Marburg, Germany
- Ph.D., 2011, Department of Chemistry, Philipps University Marburg, Germany
- Lab leader, 2011-2012, Department of Chemistry, Philipps University Marburg, Germany
- Postdoctoral research fellow, 2012-2016, Institute of Biological Chemistry, Academia Sinica, Taiwan
- Visiting Assitant Professor, 2016-2022, Taiwan Protein Project, Institute of Biological Chemistry, Academia Sinica, Taiwan
- Assistant Professor, 2022-present, Department of Chemistry, National Taiwan University, Taiwan
榮譽事項
- Academia Sinica Postdoctoral fellowship. 2013–2015.
- Best presentation award at the CNDY 2013 workshop. 2013.
- 3rd prize in the poster contest during the IITC Symposium. 2011.
- DAAD La Caixa grant for Spanish post-graduate students in Germany. 2006-2008.
- Excellence Prize in the E-MeP-Lab Master class workshop “System approaches to membrane proteins”. 2007
研究內容
代表著作
- Maestre-Reyna M, Yang C-H, Nango E, Hang W-C, Putu EPGN, Wu W-J, Wang P-H, Franz-Badur S, Saft M, Emmerich H-J, Wu H-Y, Lee C-C, Huang K-F, Chang Y-K, Liao J-H, Weng J-H, Gad W, Chang C-W, Pang AH, Sugahara M, Owada S, Hosokawa Y, Joti Y, Yamashita A, Tanaka R, Tanaka T, Luo FJ, Tono K, Kiontke S, Schapiro I, Spadacini R, Royant, A, Yamamoto J, Iwata S, Essen L-O*, Bessho Y*, Tsai M-D*. Serial crystallography captures dynamic control of sequential electron and proton transfer events in a flavoenzyme. 2022 Nature Chemistry 14, 677–685.
- Maestre-Reyna M, Huang W-C, Wu W-J, Singh PK, Hartmann R, Wang P-H, Lee C-C, Hikima T, Yamamoto M, Bessho Y, Drescher K, Tsai M-D, Wang AH-J*, Vibrio cholerae biofilm scaffolding protein RbmA shows an intrinsic, phosphate-dependent autoproteolysis activity. 2021 IUBMB Life. 73, 418–431.
- LinWu S-W, Tu Y-H, Tsai T-Y, Maestre-Reyna M, Liu M-S, Wu W-J, Huang J-Y, Chi H-W, Chang W-H, Chiou C-F, Wang A-HJ, Lee J*, Tsai M-D*, Thermococcus sp. 9°N DNA polymerase exhibits 3′-esterase activity that can be harnessed for DNA sequencing. Communications Biology 2019 Jun; 2, 224.
- Franz S, Ignatz E, Zielosko H, Putu EPGN, Maestre-Reyna M, Tsai M-D, Yamamoto J, Mittag M, Essen L-O*, Structure of the bifunctional cryptochrome aCRY from Chlamydomonas reinhardtii. Nucleic Acid Research. 2018 Sep; 6;46(15):8010-8022.
- Maestre-Reyna M, Yamamoto J, Huang W-C, Tsai M-D, Essen L-O, Bessho Y*, Twist and turn: a revised structural view on the unpaired bubble of class II CPD photolyase in complex with damaged DNA. IUCrJ. 2018 Aug; 5(Pt 5):608-618.
- Lee, C-C+, Maestre-Reyna, M+, Hsu, K-C, Wang, H-C, Liu, C-I, Jeng, W-Y, Lin, L-L, Wood, R, Chou, C-C, Yang, J-M, Wang, AH-J.* Crowning Proteins: Modulating the Protein Surface Properties using Crown Ethers. Ang. Chem. Int. Ed. 2014 Oct; 53(48):13054-8
- Maestre-Reyna, M, Diderrich, R, Veelders, M S, Eulenburg, G, Kalugin, V, Brückner, S, Keller, P, Rupp, S, Moesch, H-U*, Essen L-O.* Structural basis for promiscuity and specificity during Candida glabrata invasion of host epithelia. PNAS 2012 Sep; 109(42):16864-9
更新日期: 2023-03-07